Abstract: [Objective] To explore the healing and complication rate of Masquelet technique for post-traumatic bone defect by a meta-analysis. [Methods] Theses on Masquelet technique for post-traumatic bone defect were
retrieved from Electronic databases, including PubMed, EMBASE SCI and
OVID from beginning to April 2018. The literature were independently
evaluated and collectively brought in by two reviewers, and then a
meta-analysis was conducted based on single-arm design for the effect
indicator as rate using STATA12.0 software. [Results] A
total of 21 studies involving 594 patients were included into this
study. The meta- analysis showed that the consolidated healing rate of
bone defects managed by Masquelet technique was of (87.8%, CI 95%：84.9%~90.4%) , while the reinfection rate proved of (9.2%, CI 95%：5.3%~14%) , and nonunion rate of (5.7%, CI 95%：2.8%~9.5%) . [Conclusion] The induced membrane technique might be effective treatment for post-traumatic bone defects, however, the risks of reinfection and nonunion could not be neglected.
Effectiveness of Masquelet technique for post- traumatic bone defects: a meta- analysis YU Qing- wen, ZHAO Dong- sheng, ZHENG Xiao- yong, LIU Dao- hong.
Ｏｒｔｈｏｐ Ｊ Ｃｈｉｎ，2018，26（24）： 2254-2259