Abstract: [Objective] To introduce the 3D printing technology applied in revision hip replacement for Paprosky type III acetabular bone defects. [Methods] From June 2014 to December 2016, 14 patients underwent revision hip replacement for primary THA failure accompanied with Paprosky type III acetabular bone defects. According to the CT scanning preoperatively, a digital model was created by CAD software. After that the entity model of the pelvis was made by 3D printing to mimic surgical operation. During the revision surgery, an individualized titanium filling block previously made by 3D printing was implanted into the acetabular bone defects to restore the the anatomical hip rotation center, and then the acetabular component was enclosed with proper initial stability. [Results] The postoperative radiographs revealed that perfect bone defect filling, righteous reconstruction of the rotation center and proper position of acetabular component were acquired in all patients. At 13 months after operation, the clinical outcomes proved satisfactory, associated with Harris score of (86.93± 4.06) and SF-36 score of (95.07± 6.34) . [Conclusion] The 3D printing technology is a powerful approach to mimic revision procedure before operation, supply an individualized titanium implants for filling bone defects, and improve the surgical efficacy and patient's satisfaction in revision hip replacement for Paprosky type III acetabular bone defects.